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Rapid homologous desensitisation and cycling of G-protein-coupled... | Download Scientific Diagram

This finding indicates impairment in the actions of cAMP downstream of effects of obesity on adrenergic receptor signaling, G-protein coupled activation of adenylyl cyclase, or cAMP levels

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Baseline measurements found that TNF-alpha and IL-1-beta levels in the APP/PS1 group of mice were much higher than the wild type group of mice