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Significant sex-differences were found for cortisone with lower levels in females compared to males ( ß = −7.04832, p = 0.045), as well as higher cortisol/11-deoxycortisol ratio ( ß = 89.302, p = 0.041) and cortisol/cortisone ratio ( ß = 0.871113, p = 0.043) in females compared to males (Fig