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Orally administered NNZ-2591 can enhance IGF-1 function in neurons by competitively binding to IGFBP-3 and normalizing IGF-1 levels in the brain (ClinicalTrials.gov, accessed September 17, 2024) (151)

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NAFLD develops in four stages, steatosis (simply a fatty liver that is thought to be largely harmless), non-alcoholic steatohepatitis (NASH