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Notably, 91.9% of the combination group lost at least 5% of baseline weight, while 53.6% lost ≥20%

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163 Their proposed mechanism describes a process by which amylin fibrillization is inhibited by low pH in the secretory vesicle, but, after exocytosis and concomitant pH increase, Zn(II) can then act to prevent fibrillization in the extracellular space