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Presented for research literature review only Takahashi N et al

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Key Points Homocysteine is associated with an increased risk of over 100 diseases or adverse outcomes which are listed at the end of this article, including almost all brain and mental health disorders, from childhood to old age, including dementia and Alzheimer’s In those with cardiovascular disease having a H score above 20 increases risk of death by almost five times, and every 5 point increase increases risk by a third