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Through regulated turnover of CREBH, ERAD orchestrates the rhythmic expression of genes involved in fatty acid oxidation, triglyceride lipolysis, and gluconeogenesis

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The main types of thiol modification that have been shown to play an important redox-dependent role include protein S-glutathionylation which is produced in the cell under physiological conditions and oxidative stress, both spontaneous and enzymatic [64,65]