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Potential health benefits of cold‐water immersion: the central role of PGC‐1α - Hohenauer - The Journal of Physiology - Wiley Online Library

3.4.3 Inactivate HSCs and inhibit HSCs proliferation The activation of HSCs is influenced by changes in the cell microenvironment, leading to metabolic reprogramming, increased collagen synthesis, decreased apoptosis, delayed senescence, and reduced immune clearance

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It was healthy, active men and women