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Finally, prolonged exposure to environmental pollutants, including fine particulate matter (PM2.5), may increase UC risk by promoting systemic inflammation and oxidative stress (Gao W

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Questions remain, though, as to whether there is causation involved – for example: do high uric acid levels cause high triglycerides, or do high triglycerides cause high uric acid?[ref] Is high uric acid just a byproduct (perhaps due to diet), or is it playing a role in causing chronic disease