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Glutathione’s Role in Antioxidant, Detox, and Immune Pathways Glutathione is the most abundant endogenous antioxidant in the brain and has an affinity for glucose and oxygen, two elements heavily involved in neuronal metabolism.1 It can support the preservation of presynaptic connections and neuronal networks.2 This tripeptide molecule plays a role in: Antioxidant activity 3 Redox Homeostasis 4 Immune system support 5 Skin health 6 Glutathione is produced in every cell, with the liver helping set overall systemic levels